SYNTap® Biomarker CSF Test

The SYNTap Test helps physicians diagnose synucleinopathies such as: Parkinson’s, DLB, Alzheimer’s with Lewy bodies, MCI, and MSA.

Enabling precision medicine for neurodegenerative disorders

This website is intended for the informational purposes of healthcare professionals.

Scientist working at the laboratory

Parkinson’s Disease

How the SYNTap Test helps improve diagnostic accuracy for various types of Parkinson's.

Lewy Body Dementia

How the SYNTap Test can improve the diagnostic challenges of Lewy body dementia.

Doctor and patient

AD with Lewy Bodies

How the SYNTap Test helps differentiate the Alzheimer's variant: AD with Lewy bodies.

Multiple System Atrophy

How the SYNTap Test helps physicians differentiate MSA from Parkinson's disease.

Scientist working with chemicals in laboratory

MCI with Lewy Bodies

How the SYNTap Test helps detect Minimal Cognitive Impairment with Lewy bodies early.

Download Spec. Sheet

Details on the SYNTap Biomarker CSF Test performance characteristics.

Amprion's scientist, Luis Concha discovering an ultra sensitive prion detection

Explore Our Science

A pioneer of Prion Detection Science®, Amprion innovates biomarker testing to accurately detect misfolded proteins associated with brain diseases.

After decades of research, Amprion is thrilled to roll out its impactful discoveries from the lab to the world. 

Please Note: Important Billing Info

To improve patient access to the SYNTap® Biomarker CSF Test, Amprion offers the following billing options:

  • List price of $1500, with courtesy billing for both Medicare and private insurance.
  • An affordable self-pay price of $995 (patients may qualify for financial assistance and/or interest-free payment options).
  • Prices are effective as of January 1, 2024, and are subject to change.


Please note: Amprion is a Medicare participating provider, however, the SYNTap test does not currently have Medicare coverage determination. Also, Amprion is not yet in network with most insurers.

The SYNTap Biomarker CSF Test has been issued a dedicated CPT® PLA code to be used when billing: 0393U.

For additional information, please visit our billing page.