Title Publication Date Publication Categories Link hf:doc_categories
Revolutionizing Multiple System Atrophy Diagnosis With Amprion’s Synuclein Seed Amplification Assay: Russell Lebovitz, MD, PhD December 18, 2024 Neurology Live video
Sensitivity and specificity of a seed amplification assay for diagnosis of multiple system atrophy: a multicentre cohort study November 21, 2024 The Lancet Neurology scientific-paper
Amprion Announces Landmark Study in The Lancet Neurology November 21, 2024 Businesswire press-release
New Biomarkers for Better Neurodegenerative Disease Diagnostics and Treatments November 14, 2024 Today’s Clinical Lab news-article
Association of CSF α-synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer’s Disease Neuroimaging Initiative study October 20, 2024 Alzheimer’s & Dementia scientific-paper
Amprion Honored to Win the 2024 BioTech Breakthrough Award ‘Clinical Diagnostics Solution of the Year’ November 19, 2024 Businesswire press-release
α-Synuclein seed amplification technology for Parkinson’s disease and related synucleinopathies July 1, 2024 Trends in Biotechnology literature-review
α-Synuclein Seed Amplification in CSF and Brain from Patients with Different Brain Distributions of Pathological α-Synuclein in the Context of Co-Pathology and Non-LBD Diagnoses July 29, 2024 Annals of Neurology scientific-paper
α-Synuclein seed amplification assay shows potential to unmask pathology and enable biologically-based therapeutic development  June 1, 2023 Movement Disorders position-paper
α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer’s disease late in the disease course and dependent on Lewy pathology burden April 26, 2024 Alzheimer’s & Dementia scientific-paper
Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies April 27, 2024 Acta Neuropathologica Communications scientific-paper
SYNTap Biomarker Test helps doctors distinguish Parkinson’s Disease from Parkinsonism in early stages April 6, 2022 PR Web press-release
Structures of α-synuclein filaments from human brains with Lewy pathology September 15, 2022 Nature scientific-paper
Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson’s disease and dementia with Lewy bodies April 7, 2021 Acta Neuropathologica Communications scientific-paper
Seed amplification assay results illustrate discrepancy in Parkinson’s disease clinical diagnostic accuracy and error rates August 17, 2023 Journal of Neurology scientific-paper
Revolutionizing Dementia Research With Synuclein Biomarker Tests August 31, 2023 Neurology Live news-article
Revised criteria for diagnosis and staging of Alzheimer’s disease: Alzheimer’s Association Workgroup June 27, 2024 Alzheimer’s & Dementia position-paper
Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC February 9, 2018 Acta Neuropathologica Communications scientific-paper
Parkinson’s is often misdiagnosed. New tests may change that. October 10, 2024 Washington Post news-article
NIH Researchers to Use Amprion CSF Test in Dementia Biomarker Validation Study August 24, 2023 Precision Medicine Online news-article
New test detects Parkinson’s biomarker before movement symptoms start April 18, 2023 Fierce Biotech news-article
New Paper Published in Alzheimer’s: Dementia: The Journal of the Alzheimer’s Association, Demonstrates Correlation Between the Presence of Misfolded α-Synuclein and Clinical Presentations of Alzheimer’s Disease February 9, 2024 PR Newswire press-release
New Insights On Alzheimer’s And What It Means For Personalized Medicine January 19, 2022 PR Web press-release
New Assay Hailed as a Game Changer for Early Parkinson’s Dx April 13, 2023 Medscape news-article
Multiple biomarkers improve diagnostic accuracy across Lewy body and Alzheimer’s disease spectra March 4, 2024 Annals of Clinical and Translational Neurology scientific-paper
Misfolded alpha-synuclein in amyotrophic lateral sclerosis: Implications for diagnosis and treatment January 25, 2024 European Journal of Neurology scientific-paper
Michael J. Fox Foundation Funds Projects to Speed Development of Quantitative Biomarkers for Parkinson’s Disease May 30, 2024 PR Newswire press-release
Lab Test May Detect Parkinson’s Disease Even Before Symptoms Appear April 17, 2023 Everyday Health news-article
Investigating alpha-synuclein co-pathology in Alzheimer’s disease by means of cerebrospinal fluid alpha-synuclein seed amplification assay February 7, 2024 Alzheimer’s & Dementia scientific-paper
Investigating alpha-synuclein co-pathology in Alzheimer’s disease by means of cerebrospinal fluid alpha-synuclein seed amplification assay February 7, 2024 Alzheimer’s & Dementia scientific-paper
How Amprion’s Test is Changing ALS, Dementia, and Parkinson’s Disease Diagnosis September 24, 2024 Life Sciences 360 podcast
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease November 6, 2021 Acta Neuropathologica Communications scientific-paper
FDA letter supports use of new alpha-synuclein assay in trials September 9, 2024 Parkinson’s News Today news-article
FDA Letter of Support Could Boost Use of Parkinson’s Biomarker in Clinical Trials September 19, 2024 360Dx news-article
FDA Issues Letter of Support for α-Synuclein Seed Amplification Assay – The Core Technology Used in Amprion’s First Commercial Test September 5, 2024 Business Wire press-release
FDA Issues Letter of Support for Alpha-Synuclein Seed Amplification Assay September 5, 2024 Clinical Lab Products news-article
Exclusive: A small San Diego biotech wants to change how Parkinson’s disease is diagnosed October 8, 2024 Endpoints news-article
Evaluation of Cerebrospinal Fluid α-Synuclein Seed Amplification Assay in Progressive Supranuclear Palsy and Corticobasal Syndrome September 20, 2024 Movement Disorders scientific-paper
Dr. Russ Lebovitz: Revolutionizing Brain Health with Early Detection September 26, 2024 Life Science Success podcast
Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy February 5, 2020 Nature scientific-paper
Detection of α-synuclein in CSF by RT-QuIC in patients with isolated rapid-eye-movement sleep behaviour disorder: a longitudinal observational study March 1, 2021 The Lancet Neurology scientific-paper
Detecting Parkinson Disease at Early Stages With Alpha-Synuclein Amplification Assay: Russell Lebovitz, MD, PhD May 11, 2023 Neurology Live video
CSF α-Synuclein Seed Amplification Assay in Patients With Atypical Parkinsonian Disorders August 29, 2024 Neurology scientific-paper
Clinicopathological correlation of cerebrospinal fluid alpha-synuclein seed amplification assay in a behavioral neurology autopsy cohort March 27, 2024 Alzheimer’s & Dementia scientific-paper
Changes in the Diagnostic Process of Alzheimer Disease: A New Era of Blood-Based Approaches December 8, 2023 HCP Live news-article
Associations between misfolded alpha-synuclein aggregates and Alzheimer’s disease pathology in vivo September 11, 2024 Alzheimer’s & Dementia scientific-paper
Association of CSF α-Synuclein Seeding Amplification Assay Results With Clinical Features of Possible and Probable Dementia With Lewy Bodies July 16, 2024 Neurology scientific-paper
Assessment of heterogeneity among participants in the Parkinson’s Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study May 1, 2023 The Lancet Neurology scientific-paper
As new Alzheimer’s biomarkers come into play, here’s where the money is going October 17, 2024 PharmaVoice news-article
Analysis of Protein Conformational Strains-A Key for New Diagnostic Methods of Human Diseases April 17, 2020 International Journal of Molecular Sciences scientific-paper
Amprion’s αSynuclein Seed Amplification Assay to be Showcased at Alzheimer’s Association International Conference® 2023 (AAIC®) July 15, 2023 PR Newswire press-release
Amprion’s αSyn Seed Amplification Assay (αS-SAA) Highlighted in 10 Presentations at AD/PD™ 2024 International Conference March 4, 2024 PR Newswire press-release
Amprion’s Parkinson’s Disease Dx Shows Strong Performance in Study April 26, 2023 360Dx news-article
Amprion wins $100K to study causes of sporadic ALS September 20, 2024 ALS Today news-article
Amprion Unveils Next-Generation SAAmplify™ Biomarker Panels to Aid in Diagnosis of Neurodegenerative Disorders at AAIC 2024 August 1, 2024 Technology Networks news-article
Amprion Unveils Next-Generation SAAmplify™ Biomarker Panels to Aid in Diagnosis of Neurodegenerative Disorders at AAIC 2024 July 29, 2024 PharmiWeb news-article
Amprion Unveils Next-Generation SAAmplify™ Biomarker Panels to Aid in Diagnosis of Neurodegenerative Disorders at AAIC 2024 July 26, 2024 Business Wire press-release
Amprion Showcases SYNTap® Biomarker Test at AD/PD™ 2023 International Conference March 27, 2023 PR Newswire press-release
Amprion launching SAAmplify as tool to help in disease diagnosis August 1, 2024 Parkinson’s News Today news-article
Amprion lands new funding to advance neurodegenerative disease diagnostics October 14, 2024 Longevity Technology news-article
Amprion Joins the Fight Against Parkinson’s Through Early Detection Testing May 23, 2019 PR Newswire press-release
Amprion Exhibits at MDS International Congress of Parkinson’s Disease and Movement Disorders in Madrid and Presents Scientific Insights On SYNTap® Test at Prion2022 Conference September 15, 2022 PR Web press-release
Amprion Clinical Laboratory Receives Accreditation from College of American Pathologists October 27, 2021 PR Web press-release
Amprion Awarded NIH Grant For Analytical Validation of SYNTap® Biomarker Test For Neurological Disease May 10, 2022 PR Web press-release
Amprion announces SYNTap™ Biomarker Test for early detection of Parkinson’s Disease (PD), Lewy Body Dementia (LBD), and Alzheimer’s Disease (AD) October 6, 2021 PR Web press-release
Amprion Announces Presentation of Findings Related to Usage of the αSynuclein Seed Amplification Assay in Recent Parkinson’s Study at 2023 AAN Annual Meeting April 21, 2023 PR Newswire press-release
Amprion Announces Initial Close of a $15M Financing to Commercialize Groundbreaking Neurologic Diagnostics October 9, 2024 Business Wire press-release
Amprion Announces Granting of European Patents for Seed Amplification Assay Platform August 15, 2023 PR Newswire press-release
Amprion Announces Collaboration with NIH Researchers on Dementia Hallmark Study August 23, 2023 PR Newswire press-release
Amprion Amplifies Neurological Diagnosis February 9, 2023 San Diego Business Journal news-article
ALS Network Announces $100,000 Research Grant Awarded to Amprion, Inc. September 12, 2024 PR Newswire press-release
Alpha-Synuclein Testing Comes of Age October 7, 2024 In Vivo podcast
Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies August 28, 2016 Annals of Clinical and Translational Neurology scientific-paper
Alpha-Synuclein Oligomers and Neurofilament Light Chain Predict Phenoconversion of Pure Autonomic Failure April 30, 2021 Annals of Neurology scientific-paper
Alpha-Synuclein Amplification Assay Aids Early Detection, With Potential to Improve Diagnosis and Treatment in Parkinson Disease April 12, 2023 Neurology Live news-article
Accurate Detection of α-Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson’s Disease in the DeNovo Parkinson (DeNoPa) Cohort February 13, 2024 Movement Disorders scientific-paper
A cross-sectional study of α-synuclein seed amplification assay in Alzheimer’s disease neuroimaging initiative: Prevalence and associations with Alzheimer’s disease biomarkers and cognitive function May 21, 2024 Alzheimer’s & Dementia scientific-paper
A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research February 1, 2024 The Lancet Neurology literature-review
A biological classification of Parkinson’s disease: the SynNeurGe research diagnostic criteria February 1, 2024 The Lancet Neurology literature-review
‘Big step forward’: New lab tests may accelerate Parkinson’s diagnosis and research April 13, 2023 CNN Health news-article
Analysis of Protein Conformational Strains-A Key for New Diagnostic Methods of Human Diseases April 17, 2020 International Journal of Molecular Sciences scientific-paper
ALS Network Announces $100,000 Research Grant Awarded to Amprion, Inc. September 12, 2024 PR Newswire press-release