Revolutionizing Multiple System Atrophy Diagnosis With Amprion’s Synuclein Seed Amplification Assay: Russell Lebovitz, MD, PhD |
December 18, 2024 |
Neurology Live |
Video |
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video |
Sensitivity and specificity of a seed amplification assay for diagnosis of multiple system atrophy: a multicentre cohort study |
November 21, 2024 |
The Lancet Neurology |
Scientific paper |
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scientific-paper |
Amprion Announces Landmark Study in The Lancet Neurology |
November 21, 2024 |
Businesswire |
Press release |
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press-release |
New Biomarkers for Better Neurodegenerative Disease Diagnostics and Treatments |
November 14, 2024 |
Today’s Clinical Lab |
News article |
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news-article |
Association of CSF α-synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer’s Disease Neuroimaging Initiative study |
October 20, 2024 |
Alzheimer’s & Dementia |
Scientific paper |
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scientific-paper |
Amprion Honored to Win the 2024 BioTech Breakthrough Award ‘Clinical Diagnostics Solution of the Year’ |
November 19, 2024 |
Businesswire |
Press release |
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press-release |
α-Synuclein seed amplification technology for Parkinson’s disease and related synucleinopathies |
July 1, 2024 |
Trends in Biotechnology |
Literature review |
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literature-review |
α-Synuclein Seed Amplification in CSF and Brain from Patients with Different Brain Distributions of Pathological α-Synuclein in the Context of Co-Pathology and Non-LBD Diagnoses |
July 29, 2024 |
Annals of Neurology |
Scientific paper |
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scientific-paper |
α-Synuclein seed amplification assay shows potential to unmask pathology and enable biologically-based therapeutic development |
June 1, 2023 |
Movement Disorders |
Position paper |
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position-paper |
α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer’s disease late in the disease course and dependent on Lewy pathology burden |
April 26, 2024 |
Alzheimer’s & Dementia |
Scientific paper |
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scientific-paper |
Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies |
April 27, 2024 |
Acta Neuropathologica Communications |
Scientific paper |
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scientific-paper |
SYNTap Biomarker Test helps doctors distinguish Parkinson’s Disease from Parkinsonism in early stages |
April 6, 2022 |
PR Web |
Press release |
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press-release |
Structures of α-synuclein filaments from human brains with Lewy pathology |
September 15, 2022 |
Nature |
Scientific paper |
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scientific-paper |
Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson’s disease and dementia with Lewy bodies |
April 7, 2021 |
Acta Neuropathologica Communications |
Scientific paper |
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scientific-paper |
Seed amplification assay results illustrate discrepancy in Parkinson’s disease clinical diagnostic accuracy and error rates |
August 17, 2023 |
Journal of Neurology |
Scientific paper |
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scientific-paper |
Revolutionizing Dementia Research With Synuclein Biomarker Tests |
August 31, 2023 |
Neurology Live |
News article |
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news-article |
Revised criteria for diagnosis and staging of Alzheimer’s disease: Alzheimer’s Association Workgroup |
June 27, 2024 |
Alzheimer’s & Dementia |
Position paper |
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position-paper |
Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC |
February 9, 2018 |
Acta Neuropathologica Communications |
Scientific paper |
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scientific-paper |
Parkinson’s is often misdiagnosed. New tests may change that. |
October 10, 2024 |
Washington Post |
News article |
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news-article |
NIH Researchers to Use Amprion CSF Test in Dementia Biomarker Validation Study |
August 24, 2023 |
Precision Medicine Online |
News article |
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news-article |
New test detects Parkinson’s biomarker before movement symptoms start |
April 18, 2023 |
Fierce Biotech |
News article |
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news-article |
New Paper Published in Alzheimer’s: Dementia: The Journal of the Alzheimer’s Association, Demonstrates Correlation Between the Presence of Misfolded α-Synuclein and Clinical Presentations of Alzheimer’s Disease |
February 9, 2024 |
PR Newswire |
Press release |
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press-release |
New Insights On Alzheimer’s And What It Means For Personalized Medicine |
January 19, 2022 |
PR Web |
Press release |
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press-release |
New Assay Hailed as a Game Changer for Early Parkinson’s Dx |
April 13, 2023 |
Medscape |
News article |
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news-article |
Multiple biomarkers improve diagnostic accuracy across Lewy body and Alzheimer’s disease spectra |
March 4, 2024 |
Annals of Clinical and Translational Neurology |
Scientific paper |
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scientific-paper |
Misfolded alpha-synuclein in amyotrophic lateral sclerosis: Implications for diagnosis and treatment |
January 25, 2024 |
European Journal of Neurology |
Scientific paper |
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scientific-paper |
Michael J. Fox Foundation Funds Projects to Speed Development of Quantitative Biomarkers for Parkinson’s Disease |
May 30, 2024 |
PR Newswire |
Press release |
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press-release |
Lab Test May Detect Parkinson’s Disease Even Before Symptoms Appear |
April 17, 2023 |
Everyday Health |
News article |
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news-article |
Investigating alpha-synuclein co-pathology in Alzheimer’s disease by means of cerebrospinal fluid alpha-synuclein seed amplification assay |
February 7, 2024 |
Alzheimer’s & Dementia |
Scientific paper |
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scientific-paper |
Investigating alpha-synuclein co-pathology in Alzheimer’s disease by means of cerebrospinal fluid alpha-synuclein seed amplification assay |
February 7, 2024 |
Alzheimer’s & Dementia |
Scientific paper |
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scientific-paper |
How Amprion’s Test is Changing ALS, Dementia, and Parkinson’s Disease Diagnosis |
September 24, 2024 |
Life Sciences 360 |
Podcast |
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podcast |
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease |
November 6, 2021 |
Acta Neuropathologica Communications |
Scientific paper |
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scientific-paper |
FDA letter supports use of new alpha-synuclein assay in trials |
September 9, 2024 |
Parkinson’s News Today |
News article |
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news-article |
FDA Letter of Support Could Boost Use of Parkinson’s Biomarker in Clinical Trials |
September 19, 2024 |
360Dx |
News article |
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news-article |
FDA Issues Letter of Support for α-Synuclein Seed Amplification Assay – The Core Technology Used in Amprion’s First Commercial Test |
September 5, 2024 |
Business Wire |
Press release |
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press-release |
FDA Issues Letter of Support for Alpha-Synuclein Seed Amplification Assay |
September 5, 2024 |
Clinical Lab Products |
News article |
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news-article |
Exclusive: A small San Diego biotech wants to change how Parkinson’s disease is diagnosed |
October 8, 2024 |
Endpoints |
News article |
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news-article |
Evaluation of Cerebrospinal Fluid α-Synuclein Seed Amplification Assay in Progressive Supranuclear Palsy and Corticobasal Syndrome |
September 20, 2024 |
Movement Disorders |
Scientific paper |
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scientific-paper |
Dr. Russ Lebovitz: Revolutionizing Brain Health with Early Detection |
September 26, 2024 |
Life Science Success |
Podcast |
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podcast |
Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy |
February 5, 2020 |
Nature |
Scientific paper |
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scientific-paper |
Detection of α-synuclein in CSF by RT-QuIC in patients with isolated rapid-eye-movement sleep behaviour disorder: a longitudinal observational study |
March 1, 2021 |
The Lancet Neurology |
Scientific paper |
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scientific-paper |
Detecting Parkinson Disease at Early Stages With Alpha-Synuclein Amplification Assay: Russell Lebovitz, MD, PhD |
May 11, 2023 |
Neurology Live |
Video |
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video |
CSF α-Synuclein Seed Amplification Assay in Patients With Atypical Parkinsonian Disorders |
August 29, 2024 |
Neurology |
Scientific paper |
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scientific-paper |
Clinicopathological correlation of cerebrospinal fluid alpha-synuclein seed amplification assay in a behavioral neurology autopsy cohort |
March 27, 2024 |
Alzheimer’s & Dementia |
Scientific paper |
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scientific-paper |
Changes in the Diagnostic Process of Alzheimer Disease: A New Era of Blood-Based Approaches |
December 8, 2023 |
HCP Live |
News article |
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news-article |
Associations between misfolded alpha-synuclein aggregates and Alzheimer’s disease pathology in vivo |
September 11, 2024 |
Alzheimer’s & Dementia |
Scientific paper |
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scientific-paper |
Association of CSF α-Synuclein Seeding Amplification Assay Results With Clinical Features of Possible and Probable Dementia With Lewy Bodies |
July 16, 2024 |
Neurology |
Scientific paper |
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scientific-paper |
Assessment of heterogeneity among participants in the Parkinson’s Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study |
May 1, 2023 |
The Lancet Neurology |
Scientific paper |
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scientific-paper |
As new Alzheimer’s biomarkers come into play, here’s where the money is going |
October 17, 2024 |
PharmaVoice |
News article |
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news-article |
Analysis of Protein Conformational Strains-A Key for New Diagnostic Methods of Human Diseases |
April 17, 2020 |
International Journal of Molecular Sciences |
Scientific paper |
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scientific-paper |
Amprion’s αSynuclein Seed Amplification Assay to be Showcased at Alzheimer’s Association International Conference® 2023 (AAIC®) |
July 15, 2023 |
PR Newswire |
Press release |
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press-release |
Amprion’s αSyn Seed Amplification Assay (αS-SAA) Highlighted in 10 Presentations at AD/PD™ 2024 International Conference |
March 4, 2024 |
PR Newswire |
Press release |
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press-release |
Amprion’s Parkinson’s Disease Dx Shows Strong Performance in Study |
April 26, 2023 |
360Dx |
News article |
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news-article |
Amprion wins $100K to study causes of sporadic ALS |
September 20, 2024 |
ALS Today |
News article |
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news-article |
Amprion Unveils Next-Generation SAAmplify™ Biomarker Panels to Aid in Diagnosis of Neurodegenerative Disorders at AAIC 2024 |
August 1, 2024 |
Technology Networks |
News article |
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news-article |
Amprion Unveils Next-Generation SAAmplify™ Biomarker Panels to Aid in Diagnosis of Neurodegenerative Disorders at AAIC 2024 |
July 29, 2024 |
PharmiWeb |
News article |
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news-article |
Amprion Unveils Next-Generation SAAmplify™ Biomarker Panels to Aid in Diagnosis of Neurodegenerative Disorders at AAIC 2024 |
July 26, 2024 |
Business Wire |
Press release |
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press-release |
Amprion Showcases SYNTap® Biomarker Test at AD/PD™ 2023 International Conference |
March 27, 2023 |
PR Newswire |
Press release |
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press-release |
Amprion launching SAAmplify as tool to help in disease diagnosis |
August 1, 2024 |
Parkinson’s News Today |
News article |
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news-article |
Amprion lands new funding to advance neurodegenerative disease diagnostics |
October 14, 2024 |
Longevity Technology |
News article |
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news-article |
Amprion Joins the Fight Against Parkinson’s Through Early Detection Testing |
May 23, 2019 |
PR Newswire |
Press release |
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press-release |
Amprion Exhibits at MDS International Congress of Parkinson’s Disease and Movement Disorders in Madrid and Presents Scientific Insights On SYNTap® Test at Prion2022 Conference |
September 15, 2022 |
PR Web |
Press release |
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press-release |
Amprion Clinical Laboratory Receives Accreditation from College of American Pathologists |
October 27, 2021 |
PR Web |
Press release |
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press-release |
Amprion Awarded NIH Grant For Analytical Validation of SYNTap® Biomarker Test For Neurological Disease |
May 10, 2022 |
PR Web |
Press release |
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press-release |
Amprion announces SYNTap™ Biomarker Test for early detection of Parkinson’s Disease (PD), Lewy Body Dementia (LBD), and Alzheimer’s Disease (AD) |
October 6, 2021 |
PR Web |
Press release |
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press-release |
Amprion Announces Presentation of Findings Related to Usage of the αSynuclein Seed Amplification Assay in Recent Parkinson’s Study at 2023 AAN Annual Meeting |
April 21, 2023 |
PR Newswire |
Press release |
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press-release |
Amprion Announces Initial Close of a $15M Financing to Commercialize Groundbreaking Neurologic Diagnostics |
October 9, 2024 |
Business Wire |
Press release |
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press-release |
Amprion Announces Granting of European Patents for Seed Amplification Assay Platform |
August 15, 2023 |
PR Newswire |
Press release |
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press-release |
Amprion Announces Collaboration with NIH Researchers on Dementia Hallmark Study |
August 23, 2023 |
PR Newswire |
Press release |
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press-release |
Amprion Amplifies Neurological Diagnosis |
February 9, 2023 |
San Diego Business Journal |
News article |
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news-article |
ALS Network Announces $100,000 Research Grant Awarded to Amprion, Inc. |
September 12, 2024 |
PR Newswire |
Press release |
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press-release |
Alpha-Synuclein Testing Comes of Age |
October 7, 2024 |
In Vivo |
Podcast |
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podcast |
Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies |
August 28, 2016 |
Annals of Clinical and Translational Neurology |
Scientific paper |
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scientific-paper |
Alpha-Synuclein Oligomers and Neurofilament Light Chain Predict Phenoconversion of Pure Autonomic Failure |
April 30, 2021 |
Annals of Neurology |
Scientific paper |
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scientific-paper |
Alpha-Synuclein Amplification Assay Aids Early Detection, With Potential to Improve Diagnosis and Treatment in Parkinson Disease |
April 12, 2023 |
Neurology Live |
News article |
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news-article |
Accurate Detection of α-Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson’s Disease in the DeNovo Parkinson (DeNoPa) Cohort |
February 13, 2024 |
Movement Disorders |
Scientific paper |
|
scientific-paper |
A cross-sectional study of α-synuclein seed amplification assay in Alzheimer’s disease neuroimaging initiative: Prevalence and associations with Alzheimer’s disease biomarkers and cognitive function |
May 21, 2024 |
Alzheimer’s & Dementia |
Scientific paper |
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scientific-paper |
A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research |
February 1, 2024 |
The Lancet Neurology |
Literature review |
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literature-review |
A biological classification of Parkinson’s disease: the SynNeurGe research diagnostic criteria |
February 1, 2024 |
The Lancet Neurology |
Literature review |
|
literature-review |
‘Big step forward’: New lab tests may accelerate Parkinson’s diagnosis and research |
April 13, 2023 |
CNN Health |
News article |
|
news-article |
Analysis of Protein Conformational Strains-A Key for New Diagnostic Methods of Human Diseases |
April 17, 2020 |
International Journal of Molecular Sciences |
Scientific paper |
|
scientific-paper |
ALS Network Announces $100,000 Research Grant Awarded to Amprion, Inc. |
September 12, 2024 |
PR Newswire |
Press release |
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press-release |