Sample Collection

Specimen Requirements and Handling

The quality of laboratory results is highly dependent on proper specimen collection and handling. Listed below are the specimen requirements and handling procedures for the SYNTap® Biomarker CSF Test processed at Amprion.

  • Specimen Type: Cerebrospinal Fluid (CSF)*
  • Volume Requirements for SYNTap® Test: ≥ 0.5 mL
  • Storage/Transport
    • Frozen† (client’s own packaging with dry ice)
    • Cold (ice pack provided in Amprion shipping kit or by clien

* CSF specimens should be collected according to the institution/clinic’s standard policies and procedures.
Frozen: preferred specimen

  1. All specimens must be clearly labeled with TWO patient identifiers.
  2. A completed specimen Test Requistion Form must be submitted with the specimen. Ensure the appropriate test is selected and the requisition is signed by an authorized individual. 
  3. Specimens can be frozen to -20°C or -80°C and shipped on dry ice or may be held refrigerated and shipped with an ice pack. Refrigerated specimens should be shipped within 24 hours of collection. 
  4. Specimens should be shipped FedEx Priority Overnight. Ship specimens for arrival on weekdays only.


Place specimen in shipping kit. Send specimen shipping kit(s) via FedEx Priority Overnight service. A pickup may be scheduled online at or by calling FedEx at 800-463-3339. 

Shipping kits may be obtained from Amprion Client Services or by ordering kits here

Questions? Call Client Services at 858-461-6338 or email

International Specimens – Shipper’s Responsibility: The shipper is required to comply with the rules and guidelines for transport of medical specimens as set forth by the United States government, the government of the country of origin, and international regulatory agencies. Failure to follow instructions for packaging and shipping specimens can result in the delay, loss, or destruction of your specimens.

Please Note: Important Billing Info

To improve patient access to the SYNTap® Biomarker CSF Test, Amprion offers the following billing options:

  • List price of $1500, with courtesy billing for both Medicare and private insurance.
  • An affordable self-pay price of $995 (patients may qualify for financial assistance and/or interest-free payment options).
  • Prices are effective as of January 1, 2024, and are subject to change.

Please note: Amprion is a Medicare participating provider, however, the SYNTap test does not currently have Medicare coverage determination. Also, Amprion is not yet in network with most insurers.

The SYNTap Biomarker CSF Test has been issued a dedicated CPT® PLA code to be used when billing: 0393U.

For additional information, please visit our billing page.