A Growing Body
of Evidence
Browse the expanding collection of published research featuring our seed amplification assay (SAA) technology.
Scientific Paper
Journal of Parkinson's Disease
Faster reaction times of CSF alpha-synuclein seed amplification assay predict the diffuse malignant subtype of Parkinson's disease at 10-year follow-up
January 29, 2026
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Journal of Parkinson's disease
Analysis of α-synuclein seed amplification assay in carriers of GBA1 and LRRK2 pathogenic variants
January 23, 2026
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Neurobiology of disease
Cerebrospinal fluid α-synuclein seed amplification assay positivity is associated with increased plasma neurofilament light chain in Alzheimer's disease
January 1, 2026
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Molecular psychiatry
In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer's disease continuum
December 14, 2025
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Movement disorders
Skin Biopsy for Phosphorylated α-Synuclein in Mild Cognitive Impairment or Dementia Due to Lewy Body Disease in a Convenience Cohort from a Subspecialty Behavioral Neurology Practice
December 9, 2025
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The Lancet Neurology
Unlocking the full clinical potential of the α-synuclein seed amplification assay
July 1, 2025
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The Lancet Neurology
Diagnostic and prognostic value of α-synuclein seed amplification assay kinetic measures in Parkinson's disease: a longitudinal cohort study
July 1, 2025
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Brain
The effect of Lewy body (co-)pathology on the clinical and imaging phenotype of amnestic patients
January 31, 2025
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Journal of Movement Disorders
Cardiac 123I-meta-iodobenzylguanidine Imaging as a Biomarker for Body-first Parkinson’s Disease: Linking Peripheral α-Synuclein to Clinical Subtyping
August 4, 2025
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Nature Communications
Two-step detection of Lewy body pathology via smell-function testing and CSF α-synuclein seed amplification
August 5, 2025
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npj Parkinson's Disease
Phosphorylated α-synuclein in CSF and plasma does not reflect synucleinopathy
August 7, 2025
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Movement Disorders
Comparison of Two α-Synuclein Seed Amplification Assays for Discrimination of Parkinson Disease and Atypical Parkinsonism
August 20, 2025
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Annals of Neurology
Cognitive Performance in Early Neuronal Synuclein Disease with Hyposmia but without Motor Disability: Association with Dopamine Deficiency and Isolated Rapid Eye Movement Sleep Behavior Disorder
July 11, 2025
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eBioMedicine
Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson's disease in the PPMI cohort
September 1, 2025
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Movement Disorders Clinical Practice
Prodromal Lewy Body Symptoms and α-Synuclein Seeding in Idiopathic Olfactory Dysfunction
September 8, 2025
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Get in the Know
Bring biological certainty to your diagnosis with Amprion's SAAmplify-ɑSYN test. Order your shipping kits today and help move your patient beyond a probable diagnosis.
