A Growing Body
of Evidence
Browse the expanding collection of published research featuring our seed amplification assay (SAA) technology.
Scientific Paper
The Lancet Neurology
Unlocking the full clinical potential of the α-synuclein seed amplification assay
July 1, 2025
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The Lancet Neurology
Diagnostic and prognostic value of α-synuclein seed amplification assay kinetic measures in Parkinson's disease: a longitudinal cohort study
July 1, 2025
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Brain
The effect of Lewy body (co-)pathology on the clinical and imaging phenotype of amnestic patients
January 31, 2025
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Journal of Movement Disorders
Cardiac 123I-meta-iodobenzylguanidine Imaging as a Biomarker for Body-first Parkinson’s Disease: Linking Peripheral α-Synuclein to Clinical Subtyping
August 4, 2025
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Nature Communications
Two-step detection of Lewy body pathology via smell-function testing and CSF α-synuclein seed amplification
August 5, 2025
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npj Parkinson's Disease
Phosphorylated α-synuclein in CSF and plasma does not reflect synucleinopathy
August 7, 2025
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Movement Disorders
Comparison of Two α-Synuclein Seed Amplification Assays for Discrimination of Parkinson Disease and Atypical Parkinsonism
August 20, 2025
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Annals of Neurology
Cognitive Performance in Early Neuronal Synuclein Disease with Hyposmia but without Motor Disability: Association with Dopamine Deficiency and Isolated Rapid Eye Movement Sleep Behavior Disorder
July 11, 2025
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eBioMedicine
Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson's disease in the PPMI cohort
September 1, 2025
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Movement Disorders Clinical Practice
Prodromal Lewy Body Symptoms and α-Synuclein Seeding in Idiopathic Olfactory Dysfunction
September 8, 2025
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Journal of Neurology
Longitudinal decline in striatal DAT binding in LRRK2 Parkinson's disease: connections with CSF α-synuclein seeding activity
September 13, 2025
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Neurology
α-Synuclein Seed Amplifications Assay in a Cohort With Cognitive Impairment Performance and Interactions With CSF and Plasma Biomarkers
October 7, 2025
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Alzheimer's & Dementia
Self- and study partner–reported cognitive decline in older adults without dementia: The role of α-synuclein and amyloid biomarkers in the Alzheimer’s Disease Neuroimaging Initiative
September 23, 2024
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Brain Communications
LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization
March 6, 2025
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Molecular Neurodegeneration
Alpha synuclein co-pathology is associated with accelerated amyloid-driven tau accumulation in Alzheimer’s disease
March 18, 2025
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Get in the Know
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